The Grange's purpose was to show farmers that their happiness depended upon education as well as prosperity, and Mary Mayo "had the power of reaching those who dwell in the farm house." Perry Mayo, her husband, who gained prominence by being elected State Senator in 1887 - 1888, encouraged her efforts. In 1900, Mary was instrumental in establishing the first women's dormitory, the Women's Building, on the Michigan State University
campus. Thirty-one years later that University built a new women's dormitory and named it in honor of Mary Mayo.