During Epaphroditus Ransom's gubernatorial term (1848-1850), the Kalamazoo Regional Psychiatric Hospital
was established. Following his term as governor, Ransom became the first president of the Michigan Agricultural Society, which was instrumental in the creation of both the Michigan State Fair
and Michigan State University
. He was also a regent of the University of Michigan
(1850-1852), a founder of the village of Augusta and a state representative (1853-1854). In 1857 President James Buchanen appointed Ransom receiver of the Kansas Osage Land Office in Fort Scott, Kansas. He died in Kansas in 1859. His body was returned to Kalamazoo, where it was interred in Mountain Home Cemetery.